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Three patients (9.6%) had metastatic disease at presentation, and a further two (6.4%) developed metastases during follow-up. Similarly, size of lesion did not affect DFS, LRDFS, or OS rates. Although there was a tendency toward a higher rate of locoregional recurrences and metastases with high-grade lesions, this was not statistically significant and did not affect DFS, LRDFS, or OS rates. Ten-year disease-free survival (DFS), locoregional disease-free survival (LRDFS), and overall survival (OS) rates were 66, 72, and 55 per cent, respectively. The disease-free, locoregional disease-free, and overall mean survival rates were 80, 81, and 97 months, respectively. No patients received adjuvant chemoradiation therapy. Surgical management consisted of wide excision or mastectomy. Of 137 resected nodes in 13 patients, none were positive for metastatic disease. Size distribution consisted of 23 (72%) lesions 5 cm or less and 9 (28%) greater than 5 cm (mean, 3 range, 1.2-17.5 cm). There were 9 low-grade (28%), 2 intermediate-grade (6%), and 21 high-grade (66%) lesions. The median age was 57 years (range, 18-91).

This yielded 32 cases of phyllodes tumors (0.37%) in 31 patients. We analyzed a comprehensive database incorporating 8567 breast cancer cases treated surgically in the Tulsa, Oklahoma, region between 19. Most general surgeons involved in breast cancer care have limited experience with phyllodes tumors.
